SIBCR's mission is to improve the health and well-being of Veterans through research and education conducted at both the Seattle and Tacoma VA Puget Sound Health Care System. SIBCR is dedicated to supporting research and education efforts by facilitating collaborative research projects with other federal agencies, voluntary health organizations, nonprofit professional societies, academic institutions and for-profit companies.
SIBCR is an Equal Opportunity Employer. No phone calls please.
Date Posted: 1/6/2020
The laboratory of Brian Kraemer seeks a talented and enthusiastic postdoc who works well with others to join our multi-disciplinary collaborative research team at the Seattle Institute for Biomedical and Clinical Research (SIBCR). Dr. Kraemer is faculty at the University of Washington School of Medicine and his laboratory is located on the VA Medical Center Campus in Seattle, Washington. The Kraemer laboratory studies the molecular genetics of neurodegenerative diseases, including Alzheimer’s disease, frontotemporal lobar degeneration, and amyotrophic lateral sclerosis. This is a full time position working on a research project supported by an NIH funded R01 grant.
We offer: a highly stimulating and collaborative scientific work environment in a large laboratory with state of the art research equipment and cutting edge microscopy facilities. Opportunities for career development are readily available and include access to the NIH sponsored Alzheimer’s Disease and related dementia training program. This position includes full benefits and compensation at the NIH stipulated pay scale for postdocs. Seattle is a dynamic city in the Pacific Northwest with easy access to both the cascade mountains and Puget Sound. Additional information about the laboratory and research setting can be found here: https://sites.google.com/uw.edu/kraemerlab/home
- A PhD in a relevant field of the biomedical science.
- Experience designing and executing well controlled experiments.
- Strong writing skills.
- Strong verbal communication skills.
- Ability to work both independently and as a cooperative part of a team.
- Authorized to work in the US
Beneficial experience/knowledge/skills may include:
- Experience in genome editing using CRIPSR/Cas9 methods.
- Experience in molecular cloning and transgenesis methods
- Experience with genetic analysis methods in model organisms.
- Experience in assessing protein aggregation.
- Experience in advanced microscopy techniques.
- Knowledge of RNA binding protein function.
- Knowledge of the pathobiology of neurodegenerative disease
- Knowledge of the biology of aging and disease
- Knowledge of neurobiology
Date Posted: 3/26/2020
Duties assigned to this title will require an in depth knowledge of a specialized field, process, or discipline and may involve organizing and implementing complex research plans, the development of methods of research, testing and data collection, analysis and evaluation, and writing reports containing descriptive, analytical, and evaluative content. The duties will require the exercise of independent discretion and judgment in carrying out research activities within the predetermined research scope and methodology.
- Knowledge of the principles and techniques of the subject disciplines.
- Organizational and project management skills.
- Written and oral communication skills.
- The incumbent will be employed to carry out advanced independent and/or directed research to achieve the objectives of the research project.
- At the time of employment, the responsible faculty member or principal investigator will establish the professional objectives and performance standards for the incumbent and will make annual evaluations.
- Collect and analyze data, including periodical/literature search and utilizing specialized skills in related field to analyze the collected data.
- Participate/assist in manuscript writing for publication in scientific journals and/or presentations. May also assist in grant writing.
- Presentation of project results to internal and external parties.
- Lab maintenance, including equipment maintenance, and ordering of supplies as needed.
- Other duties as assigned, which may include attending Scientific Conferences and Meetings.
- A doctoral degree in the appropriate field or discipline.
- Must provide three professional references
Date Posted: 8/26/2020
This position is located in the Research and Development (R&D) Service at VA Puget Sound Health Care System (VAPSHCS), Seattle, WA. Research Program Lab Ops Managers are primarily responsible for the management of R&D Laboratory space, equipment, and supplies.
This is an R&D core position that serves as a resource to Principal Investigators (PI) and collaborators by providing information collection and management of laboratory operations, training and guidance to investigators and project staff in the host institution and affiliated or collaborating institutions.
The Lab Ops Manager performs research support activities such as lab operations systems services (installation, configuration and maintenance) consultation and/or direct assistance to department faculty, staff and administrators regarding biomedical and laboratory management and resource availability.
Laboratory Operational Activities:
- Tracking, reporting, and arranging laboratory equipment maintenance agreements and business activities
- Training and educating PIs and staff in the use and availability of laboratory equipment and space
- Ensuring compliance with various lab business processes and customer support including quality assurance and laboratory study applications consultation and support
- Ordering and coordinating laboratory supply and equipment orders for R&D
- Overseeing staff who track inventory and support needs for biomed laboratory studies
- Serving as a service COR, and purchase card holder
- Configuring networked research equipment, troubleshooting and resolving any network issues related to these, as well as ensuring that stakeholders have the appropriate documentation in place to ensure that these systems remain compliant with VA policy and national law.
- Tracking, coordinating, and managing the various moves of the research labs, and ensuring that the various key stakeholders, including PI’s and R&D leadership are informed as to the status of these moves
Laboratory and Clinical Research Support:
- This includes collaboration and/or active study participation with principal investigators, project directors and various analytical, technical or supporting staff
- The Lab Ops Manager also provides critical business support and specialty services, drawing on technical education and practical experience in both laboratory and clinical research and IT-based environments
- Support assignments consist of a substantial number and variety of duties as needed
- Make decisions regarding what needs to be done include the assessment of new or unusual circumstances, variations in approach and incomplete or conflicting information
- Involved with planning, coordination and problem resolution are affected by the need to keep up to date on the specialized information needs of users, the increasing quantity of information available, and changes in the means of accessing and disseminating laboratory space for the researchers
- The Lab Ops Manager maintains regular contacts with Principal Investigators, Project Directors, project staff such as technical, support, and allied health professionals, and administrative staff at the VAPSHCS, affiliate university (University of Washington), SIBCR and participating/collaborating sites
- Maintain contacts with supervisors ensure coordination of effort and provide guidance and assistance to the PI and Project Director
- Contacts with other project staff provide the opportunity to train and assist them in working continually, consistently, and safely
- Contacts with professional colleagues provide opportunity to keep abreast of the most recent developments in the fields of interest, to exchange information, and coordinate R&D scientific and business activity
The Lab Ops Manager reports to the lead Lab Operations tech for R&D who defines the Lab Ops Managers continuing areas of responsibility and/or long-term assignments and sets the general objectives. The Lab Ops Manager plans and carries out the work with a high degree of autonomy, ethically and creatively resolves any conflicts and problems that arise, coordinates work with others and interprets policies with little supervision, and at his/her own initiative. The Lab Ops Manager determines the approach to be taken and the methods to be used and keeps the supervisor informed of progress, controversial issues and issues with far-reaching implications and problems which represent a significant departure from research or business plans and objectives are brought to the supervisor's attention with recommendations for solution. The Lab Ops Manager applies his/her professional knowledge and ability in performing those aspects of the research assigned. Performance is reviewed in terms of the appropriateness, effectiveness, compatibility with other information program requirements and effectiveness in meeting objectives and expected results.
The purpose of the work is to support the investigators in the various research labs. This position requires specialized information and the ability to independently locate information, or develop corrective approaches relevant to the user’s needs; often without available established practices and techniques. The work directly affects the ability of researchers to perform their missions.
The work is often physical and demands a daily presence in multiple laboratories and buildings. The incumbent should have good communications ability and have sufficient mobility to visit laboratory sites as needed. The work often involves walking, standing, bending, or the carrying of 50-100 lb. items. The Lab Ops Manager will work mostly within office and/or research facility environments (i.e. labs). The work involves visits to clinical, laboratory and/or filed settings for purposes of training, consultation and assistance activity.
The Lab Ops Manager must protect printed and electronic files containing sensitive data in accordance with the provisions of the Privacy Act of 1974 and other applicable laws, Federal regulations, VA statutes and policy, and VHA policy. Protects the data from unauthorized release or from loss, alteration, or unauthorized deletion. Follows applicable regulations and instructions regarding access to computerized files, release of access codes, etc., as set out in the computer access agreement that the employee signs.
It is the Lab Ops Manager’s responsibility to be safety conscious, to be alert to recognize hazardous conditions and to do what is possible to eliminate or assist in eliminating these conditions; or, if that cannot be done, to work safely within them; to avoid committing unsafe acts; and to be watchful of the safety of employees for mutual protection. The incumbent is to report all unsafe working conditions immediately to the supervisor and is encouraged to apply his/her training and experience to planning better methods and arrangements.
Knowledge and Experience:
Knowledge of a wide range of techniques, methods, sources and procedures for laboratory maintenance and management related to research projects and studies in order to modify standard information practices, precedents and techniques, adapt laboratory procedures and apply standard practices and disciplines as they relate to the subject studies.
- Knowledge of, and experience in, a biological, clinical or allied health sciences facilities and maintenance
- Familiarity/experience with federal medical centers including knowledge of Federal data security and lab safety regulations and mandates
- Knowledge of federal procurement practices, to ensure compliance with applicable laws, during procurements
- Knowledge of basic equipment networking, preventative maintenance, and corrective maintenance techniques
- Skill in oral and written communication
- Knowledge of guidelines include safety practice and data security in biomedical, clinical, health services and/or clinical sciences, and IT and communications system. The guidelines are not always completely applicable and require the Lab Ops Manager to adapt or develop methods to meet unique situations. Agency policies and procedures regarding the conduct of research studies, protection of sensitive data, etc., are followed.