SIBCR's mission is to improve the health and well-being of Veterans through research and education conducted at the both the Seattle and Tacoma VA Puget Sound Health Care System. SIBCR is dedicated to supporting research and education efforts by facilitating collaborative research projects with other federal agencies, voluntary health organizations, nonprofit professional societies, academic institutions and for-profit companies.
SIBCR is an Equal Opportunity Employer. No phone calls please.
Date Posted: 9/25/18
The Garcia laboratory in the Department of Medicine at the University of Washington and the VA Puget Sound is looking for a highly motivated postdoctoral fellow, who is interested in studying signaling networks related to mitochondria and muscle wasting in cancer patients and in skeletal muscle samples.
The research team is interested in elucidating comprehensive signaling networks that control muscle mass and function with the goals to identify and characterizing novel mechanisms of muscle atrophy in the setting of cancer. We are particularly interested in the role of mitochondria and hormonal signaling including androgens.
Applicants should have a Ph.D. degree or equivalent in the field of the life sciences, a strong publication record, and good spoken/written communication skills.
Backgrounds/skills include expertise in: 1) Clinical/translational research, 2) Muscle metabolism and mitochondrial function, and 3) molecular biology in cancer or metabolic diseases. The postdoctoral fellow will work in a highly interactive laboratory environment and collaborate with clinical experts, molecular biologists, and biochemists.
Date Posted: 2/21/19
This posting is for a research assistant position in the labs of Drs. Michelle Erickson and William Banks at the Seattle VA Medical Center. The scientific focus of the labs comprises many aspects of blood-brain barrier physiology that include peptide and protein transport, neuroimmune communication, and perturbation by pharmacologic agents, inhaled toxicants, and disease states such as Alzheimer’s disease. This position is temporary (1-2 years), with extension/renewal possible depending on the applicant’s performance, lab needs, and funding. Applicants who wish to gain post-baccalaureate research experience to strengthen their application for an advanced degree program would be well-suited for this position.
- Carry out technical aspects of research projects, which includes designing and conducting experiments, recording and managing data, and communicating results to supervisors and the research group
- Complete and stay current on all training required by the VA and affiliated institutions and adhere to all rules and regulations
- More detailed aspects of technical duties:
- Maintain cell cultures, including iPSC lines and in vitro models of the blood-brain barrier
- Conduct pharmacokinetic studies of peptide and protein transport across the blood-brain barrier in vitro and in vivo
- Assist with tissue dissections and sample processing
- Quantify levels of proteins and mRNA in tissues using procedures such as immunoblotting, ELISA, immunofluorescent analysis and microscopy, qPCR, etc.
- Perform cloning projects for the development of viral vectors
- Must be able to commit 40 hours a week
- Must be willing to occasionally work evenings and weekends when needed
- Must be willing to work with mice and radioactive isotopes and strictly adhere to all regulations regarding their use
- Must be legally authorized to work in the US
- Must work well with others, be pro-active about seeking help when needed, and respect all members in the lab
Knowledge and Experience:
- Bachelor’s degree in biology or a related academic program in the life sciences (exceptional candidates in their senior year with a low burden of coursework may be considered)
- Prior wet lab experience, including cell culture and experience with molecular biology techniques preferred.
Date Posted: 3/7/19
This posting is for a full-time Research Assistant (RA) in the lab of Dr. Melanie Harned at the VA Puget Sound, Seattle Division. The RA will work on a National Institute of Mental Health-funded study evaluating pragmatic methods of assessing fidelity to Dialectical Behavior Therapy (DBT) in community practice settings. This position is temporary (1 year). This is an ideal opportunity for individuals interested in gaining additional research experience before applying to graduate school in psychology or related fields. There may also be opportunities to present at national conferences and assist in the development of manuscripts.
Under minimal supervision and guidance:
- Assists with recruitment and consenting of study participants
- Oversees enrollment, retention, and tracking of all study participants
- Functions as the liaison between study participants and study staff
- Tracks and schedules all assessments and research activities
- Monitors data collection and conducts quality assurance audits
- Manages and enters data
- Monitors receipt and storage of confidential files and audio-video recordings
- Performs related duties as required
- Bachelor’s degree in psychology or related field
- Full-time (40 hours/week)
- One-year commitment
- Previous research experience, including consenting research participants
- Ability to work independently as well as within a team
- Experience with data management and statistical software
- Excellent oral and written communication skills
- Strong problem-solving skills
- Very detail-oriented
This position will begin in June or July 2019.
Date Posted: 3/19/19
The Research Coordinator will be working in complex research studies and will aid in research development, data collection, and other activities to carry out research program goals.
- Conduct patient screenings through review of electronic medical charts
- Schedule and complete research testing as outlined in protocols in several Seattle area hospitals such as Puget Sound VA, Fred Hutchinson Cancer Center, UW Medical Center
- Keep accurate report of research data
- Blood drawing/processing, biopsy tissue handling/processing
- Intramuscular administration of medications
- Muscle function assessment of elderly research patients
- Maintain regulatory/compliance paperwork
- Attention to detail
- Great organizational skills
- Ability to multi-task
- Works well with a team and independently
- Motivated to be involved in research activities
- Able to travel within the Seattle area
- Phlebotomy certification preferred
- Able to provide intramuscular injections preferred
- Daily hours are somewhat flexible based on schedule of the day, but consistent early morning availability is preferred
Knowledge and Experience:
- Proficient with Microsoft Office package (especially Outlook, Excel, and Word)
- Prior volunteer/work experience in research is preferred (human research is also preferred)
Date Posted: 3/19/19
The Research Technician will work in a large, successful group focused on muscle wasting research. Responsibilities will include working both independently and as a member of a team with multiple technicians, post-doctoral fellows and principal investigators, and providing technical assistance with ongoing research projects. Duties will focus on managing mouse colonies, performing animal physiology studies and ex-vivo work with rodent and human samples.
- Monitor and record animal weights as well as food and water consumption.Tumor implantation and administration of injections on conscious and anesthetized animals.
- Measuring body composition, grip strength, treadmill performance and CLAMS use in mice.
- Be responsible for mouse breeding, including genotyping.
- Perform and assist with survival and non-survival surgical procedures.
- Perform tissue collection and prepare tissue for subsequent analysis (e.g. histology, biochemical assay).
- Maintain detailed records, schedule mouse studies and analyze data.
- Perform regular presentations of data to the research group.
- Practice humane use, care and treatment of animals in accordance with federal regulations and as approved by the facility's animal care committee.
- Performance of molecular assays (PC, western, ELISA, immunohistochemistry) in human and animal samples.
- Provide general up keep in the laboratory and in the animal facility.
- Perform other related duties as assigned.
- Maintenance of training and certifications as required by the facility.
- Training is provided and after further training more duties and responsibilities to be assigned.
This job requires the individual to be motivated, well organized and have good attention to detail. The person in the Research Technician position must be willing to work 20-40 hours/week, on a five day/week (M-F) daytime schedule with occasional weekend or evening hours as needed.
- Bachelor's degree in physiology or related field.
- Experience in cell culture, immunostaining and histology would be beneficial.
- Proficiency in using Microsoft Office, particularly design and use of spreadsheets is desirable.
Knowledge and Experience:
One to three years of relevant experience with research mice.