SIBCR's mission is to improve the health and well-being of Veterans through research and education conducted at both the Seattle and Tacoma VA Puget Sound Health Care System. SIBCR is dedicated to supporting research and education efforts by facilitating collaborative research projects with other federal agencies, voluntary health organizations, nonprofit professional societies, academic institutions and for-profit companies.
Equal Employment Opportunity Policy
The Seattle Institute for Biomedical and Clinical Research does not discriminate in employment on the basis of race, color, religion, sex (including pregnancy), gender identity or status as transgender, national origin, political affiliation, sexual orientation, marital status, disability, genetic information, age, membership in an employee organization, retaliation, parental status, military service, or other non-merit factor protected by federal, state or local law. Click here for more information from EEOC | E-Verify Participant | Immigrant and Employee Rights
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Date Posted: 1/6/2020
The laboratory of Brian Kraemer seeks a talented and enthusiastic postdoc who works well with others to join our multi-disciplinary collaborative research team at the Seattle Institute for Biomedical and Clinical Research (SIBCR). Dr. Kraemer is faculty at the University of Washington School of Medicine and his laboratory is located on the VA Medical Center Campus in Seattle, Washington. The Kraemer laboratory studies the molecular genetics of neurodegenerative diseases, including Alzheimer’s disease, frontotemporal lobar degeneration, and amyotrophic lateral sclerosis. This is a full time position working on a research project supported by an NIH funded R01 grant.
We offer: a highly stimulating and collaborative scientific work environment in a large laboratory with state of the art research equipment and cutting edge microscopy facilities. Opportunities for career development are readily available and include access to the NIH sponsored Alzheimer’s Disease and related dementia training program. This position includes full benefits and compensation at the NIH stipulated pay scale for postdocs. Seattle is a dynamic city in the Pacific Northwest with easy access to both the cascade mountains and Puget Sound. Additional information about the laboratory and research setting can be found here: https://sites.google.com/uw.edu/kraemerlab/home
- A PhD in a relevant field of the biomedical science.
- Experience designing and executing well controlled experiments.
- Strong writing skills.
- Strong verbal communication skills.
- Ability to work both independently and as a cooperative part of a team.
- Authorized to work in the US
Beneficial experience/knowledge/skills may include:
- Experience in genome editing using CRIPSR/Cas9 methods.
- Experience in molecular cloning and transgenesis methods
- Experience with genetic analysis methods in model organisms.
- Experience in assessing protein aggregation.
- Experience in advanced microscopy techniques.
- Knowledge of RNA binding protein function.
- Knowledge of the pathobiology of neurodegenerative disease
- Knowledge of the biology of aging and disease
- Knowledge of neurobiology
Date Posted: 11/4/20
The Research Coordinator will play an integral role in ongoing, multicenter research studies on Parkinson’s disease based at the Seattle VA Medical Center. This individual will participate in subject screening and recruitment, collection of clinical information, procurement of biological specimens, medical records review, and data coding/entry. Travel offsite may be required periodically.
Under minimal supervision, this individual will:
- Screen subjects for eligibility criteria
- Obtain informed consent from study participants
- Collect clinical information from interviews with study participants
- Conduct neuropsychological testing and gait assessment
- Enter clinical information and test results into database
- Perform venipuncture and assist lumbar puncture
- Process biospecimen
- Schedule visits for study participants
- Coordinate projects with other research groups
- Maintain contact with physicians and community organizations for recruitment
- Manage and complete IRB and other administrative study forms
- Facilitate study site visits and ensure all required documentation is available for auditors and monitors
- Ensure that projects are executed successfully and completed within required time frames to meet research objectives
Four years of college-level course work in relevant academic areas and previous Research Coordinator experience.
- Experience working with the geriatric population
- Experience working with dementia and/or decision impaired populations
- Fundamental understanding of Parkinson’s disease
- Ability to work independently, strong interpersonal skills
- A strong working knowledge of Microsoft Access and Excel software
Date Posted: 11/9/20
The Research Coordinator will be working in complex research studies and will aid in research development, data collection, and other activities to carry out research program goals. This will involve primarily in-person research and the ability to work on site 40 hours per week.
- Conduct patient screenings through review of electronic medical charts
- Schedule and complete research testing as outlined in protocols in several Seattle area hospitals such as Puget Sound VA, Fred Hutchinson Cancer Center, UW Medical Center
- Keep accurate report of research data
- Blood drawing/processing, biopsy tissue handling/processing
- Intramuscular administration of medications
- Muscle function assessment of elderly research patients
- Maintain regulatory/compliance paperwork
- Attention to detail
- Great organizational skills
- Ability to multi-task
- Works well with a team and independently
- Motivated to be involved in research activities
- Able to travel within the Seattle area
- Phlebotomy certification preferred
- Able to provide intramuscular injections preferred
- Daily hours are somewhat flexible based on schedule of the day, but consistent early morning availability is preferred
Knowledge and Experience:
- Proficient with Microsoft Office package (especially Outlook, Excel, and Word)
- Prior volunteer/work experience in research is preferred (human research is also preferred)
Hourly/Non-Exempt (12-15 hours a week)
RESEARCH ASSISTANT - IJ
This is for a part-time Research Assistant position, working 12-15 hours per week. The Research Assistant will provide technical support in a laboratory involved in research of the cellular and molecular processes underlying traumatic brain injury (TBI) and neurodegenerative diseases, such as Alzheimer’s and Parkinson’s disease through study of the human brain and animal models. This position will involve bench research techniques including immunofluorescence, fluorescence microscopy, primary cell culture, and image analysis. It will also involve work with mice, including breeding, surgical procedures, and behavioral studies.
- Handle mice, maintain mouse breeding colony, collect tissue for genotyping, perform mouse surgical procedures
- Help maintain animal inventory records.
- Tissue collection, processing, sectioning, staining and immunohistological labeling, and imaging.
- Analysis of acquired images using programs such as ImageJ.
- Organize and maintain data records in lab notebooks and in computer spreadsheets, graph and perform statistical analysis on results.
- Present results to PI and other lab members in group settings.
- Participate in lab discussions of research journal articles and other relevant topics.
- Operate standard lab equipment such as microscopes, centrifuges, balances, and pH meters.
- Make laboratory solutions and prepare supplies for group use.
- Help maintain equipment in good working order.
- Work as a member of a team but must be able to work independently in the laboratory and animal facility.
- Assisting lab members in a variety of laboratory techniques as required/assigned, such as PCR, mouse behavioral testing, or tissue culture.
- Assist with other lab maintenance tasks, such as cleaning, ordering, onboarding of new lab members, and preparation for lab safety inspections.
- Experience handling and working with mice.
- Minimum of 1 year experience in a laboratory setting, academic or employment situations.
- Minimum of 2 years of college level education with a background in biological sciences.
- Ability to work in a team AND independently, reporting significant issues as necessary.
Knowledge and Experience:
Experience working in a laboratory setting; experience working with mice; knowledge of good laboratory and safety practices; experience working with standard laboratory equipment; good written and verbal communication skills.